Six Killed in Snowy Conditions in Midwest Winter Storm (PHOTOS)

This week's winter storm is being blamed for six deaths after snow made travel conditions treacherous in the Midwest and Plains Monday and Tuesday.

Two deaths were confirmed in separate crashes Tuesday in Ohio on roads made snowy and icy by the winter storm. There were also two large pileups involving at least 50 vehicles each in Ohio on Tuesday, but no deaths were reported in those incidents.

Three were killed Monday morning near the town of Charlotte, Michigan, about 100 miles northwest of Detroit, in a head-on collision, as the area received up to 4 inches of snow. Police reported that weather conditions were a factor in the accident.

In northeastern Kansas, an 8-year-old girl was killed when a truck crashed into the car in which she was travelling after sliding on ice on U.S. Highway 56.

(MORE: 6 Killed on Slick Roads as Snowstorm Hits Plains, Midwest)

The storm, named Winter Storm Caleb by The Weather Channel, caused travel headaches throughout the Midwest Monday. Several crashes blocked lanes on Interstate 80 in central Iowa, and southbound Interstate 39 near Beloit, Wisconsin, was closed for about two and a half hours due to a number of accidents.

At Chicago's O'Hare International Airport, an American Airlines flight slid off the icy runway Monday morning. No one was injured.

The snow forced more than 1,400 flight cancellations at Chicago's two big airports alone on Monday, according to the flight-tracking website FlightAware.

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